Description
MOTS-C 10mg is a 10mg vial of MOTS-c, a mitochondrial-derived peptide, supplied by Ameano Peptides as freeze-dried powder. It’s sold for laboratory research only.
About MOTS-c
MOTS-c is a 16-amino-acid peptide encoded in the mitochondrial 12S rRNA gene. It was described in 2015 by Pinchas Cohen’s group at USC.
It acts on metabolism, in part through AMPK.
How MOTS-c acts in the lab
Most proteins are coded in the cell nucleus. MOTS-c is one of a handful of peptides coded in mitochondrial DNA instead. Its main target looks like the folate cycle, which feeds into AMPK activation and better glucose handling in muscle.
Under stress it can move into the nucleus and change gene expression. Circulating levels drop with age in both mice and people, which is why it’s studied in metabolism and aging.
MOTS-C 10mg specifications
- Compound: MOTS-c
- CAS number: 1627580-64-6
- Molecular formula: C101H152N28O22S2
- Molar mass: 2,174.6 g/mol
- Sequence: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg
- Amount: 10mg per vial
- Form: lyophilized (freeze-dried) powder
- Purity: 99% or higher (HPLC)
- SKU: AMP-MOTSC-10
- Use: laboratory research only
MOTS-c research
Lee and colleagues reported in Cell Metabolism (2015) that MOTS-c prevented diet-induced obesity and insulin resistance in mice.
Reynolds and colleagues showed in 2021 that it improved physical capacity in young, middle-aged and old mice.
To read the papers yourself, start with this PubMed search for MOTS-c.
MOTS-C 10mg purity and testing
Every batch of MOTS-C 10mg is made to a minimum of 99% purity by HPLC.
The label on every vial shows the compound, the amount and the batch. Ask us for the certificate of analysis for your batch and we’ll email it over, which is handy if your lab keeps paperwork on file.
Write the batch number in your lab notes when you open a new vial. If you ever need to compare results between orders, that’s the detail you’ll want.
Reconstituting MOTS-C 10mg
Concentration is just the amount in the vial divided by the liquid you add. With 10mg in this vial:
- 1mL of diluent gives 10mg/mL
- 2mL of diluent gives 5mg/mL
- 3mL of diluent gives 3.33mg/mL
Pick the volume that keeps your own calculations simple, then write the concentration and the mixing date on the label.
Research diluent solution or bacteriostatic water both work. Add it slowly so it runs down the side of the vial, then swirl or roll until everything dissolves. Shaking can shear peptide chains. Skip it.
Storing MOTS-C 10mg
Unopened, keep MOTS-C 10mg in a fridge at 2 to 8°C, or in a freezer at -20°C if it’ll be a while before you use it. Keep it out of direct light. Once mixed, keep it refrigerated and use it within about four weeks.
Setting up for MOTS-C 10mg
You’ll need a diluent to mix MOTS-C 10mg. Our 10mL research diluent covers several vials, and the 2mL diluent kit gives you a fresh vial for each mix. Add sterile syringes and alcohol swabs, and the 10-slot vial case if you want your vials stored upright in the fridge.
MOTS-C 10mg bulk pricing
You can buy MOTS-C 10mg one vial at a time or in a multi-pack. The options in the dropdown are:
- Single vial: $54.00
- 5 pack: 5 vials for $243.00 instead of $270.00, about $48.60 a vial
- 10 pack: 10 vials for $459.00 instead of $540.00, about $45.90 a vial
Multi-packs ship as separate sealed vials, so you only open what you need. Unopened ones keep in the fridge or freezer until you get to them.
Related research peptides
- AMP-2P 60mg, a GIP/GLP-1 agonist
- Lipo-C with B12 10mL, a lipotropic solution
- AMP-1P 5mg, a GLP-1 agonist
- AMP-3P 12mg, a triple agonist
- AOD-9604 5mg, a hGH fragment
Browse the full weight loss peptides and anti-aging peptides range, or see everything on our research peptides page.
MOTS-C 10mg questions
How much is in the MOTS-C 10mg vial?
10mg of lyophilized powder. The amount is printed on the label.
Can MOTS-c be used in people or animals?
No. It’s sold for laboratory research only and isn’t approved for human or veterinary use.
Is MOTS-C 10mg in stock?
Yes, MOTS-C 10mg is in stock now and ready to ship.
Is there a COA for MOTS-C 10mg?
Yes. Each batch has a certificate of analysis filed under the batch number on the label. Email us that number and we’ll send it.
Is there a discount for buying more?
Yes. The 5 pack saves 10% and the 10 pack saves 15% compared with buying single vials. Pick the option from the dropdown on this page.
Buy MOTS-C 10mg from Ameano Peptides
Order MOTS-C 10mg now for $54.00. It’s in stock, and checkout takes about two minutes. Add a research diluent solution if you don’t have any, so you’re ready to reconstitute when it arrives.
Need more for the same project? See the rest of our weight loss peptides and anti-aging peptides.
For laboratory research use only. Not for human or veterinary use. Not evaluated by the FDA.
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