Description
AMP-3P 12mg from Ameano Peptides is 12mg of AMP-3P (retatrutide) in a sealed glass vial. AMP-3P is a GIP, GLP-1 and glucagon receptor agonist. It’s intended for lab research only.
What is AMP-3P (retatrutide)?
Retatrutide (LY3437943, often sold as GLP-3R) is a single peptide from Eli Lilly that acts on three receptors: GIP, GLP-1 and glucagon.
It’s still in clinical trials.
AMP-3P mechanism of action
Retatrutide hits three receptors with one peptide: GIP, GLP-1 and glucagon. The first two are incretins that boost glucose-dependent insulin release and, in GLP-1’s case, curb appetite and slow stomach emptying.
The glucagon part is the unusual bit. Glucagon raises energy expenditure and pushes the liver to burn fat, so pairing it with the incretins is meant to work on both sides of energy balance. That’s the main reason researchers compare it with the dual and single agonists.
AMP-3P 12mg specifications
- Compound: AMP-3P (retatrutide)
- Also known as: LY3437943
- CAS number: 2381089-83-2
- Molar mass: 4,731.3 g/mol
- Structure: 39 amino acids with a fatty diacid side chain
- Amount: 12mg per vial
- Form: lyophilized (freeze-dried) powder
- Purity: 99% or higher (HPLC)
- SKU: AMP-3P-12
- Use: laboratory research only
What the research says about AMP-3P
Jastreboff and colleagues reported in the New England Journal of Medicine (2023) a mean weight loss of up to 24% at 48 weeks in a phase 2 trial.
Phase 3 trials are under way.
The primary literature is on PubMed. Here’s a search for retatrutide studies to start from.
Reconstituting AMP-3P 12mg
The volume of liquid you add sets the concentration. For a vial holding 12mg:
- 1mL of diluent gives 12mg/mL
- 2mL of diluent gives 6mg/mL
- 3mL of diluent gives 4mg/mL
Go with whichever number is easiest to work with in your protocol, and label the vial with the concentration and the date you mixed it.
Most labs use sterile bacteriostatic water or our research diluent solution. Let the vial reach room temperature, run the liquid slowly down the inside of the glass, then roll it gently until the powder dissolves. Don’t shake it. Shaking can shear peptide chains.
How to store AMP-3P 12mg
The dry powder keeps best cold: 2 to 8°C in the fridge, or -20°C for long-term storage. After reconstitution, store it in the fridge and finish it within roughly four weeks.
AMP-3P 12mg quality and batch records
AMP-3P 12mg is sold at 99% purity or better, measured by HPLC. That figure is the minimum for every batch we ship, not a best case.
Look for the batch number on the label. That’s what the certificate of analysis is filed under, and we’ll send you the COA for it on request.
Keep the batch number with your records. It’s the quickest way to match a vial to its paperwork later.
What you need with AMP-3P 12mg
Check you have everything before the vial arrives: a sterile diluent such as our research diluent solution, sterile syringes, alcohol swabs and room in the fridge. Our vial case holds ten vials upright, and the vial opener pops flip-off caps cleanly.
AMP-3P 12mg bulk pricing
You can buy AMP-3P 12mg one vial at a time or in a multi-pack. The options in the dropdown are:
- Single vial: $52.00
- 5 pack: 5 vials for $234.00 instead of $260.00, about $46.80 a vial
- 10 pack: 10 vials for $442.00 instead of $520.00, about $44.20 a vial
Multi-packs ship as separate sealed vials, so you only open what you need. Unopened ones keep in the fridge or freezer until you get to them.
AMP-3P sizes compared
- AMP-3P 6mg: 6mg for $39.00, about $6.50 per mg
- AMP-3P 10mg: 10mg for $44.00, about $4.40 per mg
- AMP-3P 12mg (this page): 12mg for $52.00, about $4.33 per mg
- AMP-3P 20mg: 20mg for $67.00, about $3.35 per mg
- AMP-3P 24mg: 24mg for $80.00, about $3.33 per mg
- AMP-3P 48mg: 48mg for $159.00, about $3.31 per mg
The middle size, AMP-3P 12mg, is a sensible default if you’re not sure how much AMP-3P your project will use.
Compounds often ordered with AMP-3P
- Reta/Cagri Blend 12.5mg/2.5mg, AMP-3P and Cagrilintide in one vial
- AMP-1P 5mg, a GLP-1 agonist
- Cagrilintide 5mg, an amylin analog
- AMP-2P 60mg, a GIP/GLP-1 agonist
- Eloralintide 10mg, an amylin agonist
Browse the full GLP-1 peptides and weight loss peptides range, or see everything on our research peptides page.
AMP-3P 12mg FAQ
How much is in the AMP-3P 12mg vial?
12mg of lyophilized powder. The amount is printed on the label.
Is AMP-3P the same as retatrutide?
Yes. AMP-3P is our product name for retatrutide research material, and the label and certificate of analysis identify it as retatrutide.
Is there a discount for buying more?
Yes. The 5 pack saves 10% and the 10 pack saves 15% compared with buying single vials. Pick the option from the dropdown on this page.
Is there a COA for AMP-3P 12mg?
Yes. Each batch has a certificate of analysis filed under the batch number on the label. Email us that number and we’ll send it.
What do I mix AMP-3P 12mg with?
A sterile diluent such as our research diluent solution or bacteriostatic water. The reconstitution section above shows the concentration for each volume.
Buy AMP-3P 12mg online
AMP-3P 12mg is in stock at $52.00. Choose a single vial or a multi-pack, add it to the cart and check out in a couple of minutes. Add a research diluent solution if you don’t have any, so you’re ready to reconstitute when it arrives.
Need more for the same project? See the rest of our GLP-1 peptides and weight loss peptides.
For laboratory research use only. Not for human or veterinary use. Not evaluated by the FDA.






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